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发表于 2008-5-25 10:56 AM
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Burger's Medicinal Chemistry and Drug Discovery Sixth Edition （6 Volumes）
Burger's Medicinal Chemistry and Drug Discovery（《Burger's 药物化学与药物发现》）第6版是Burger纪念版，Alfred Burger（1905－2000）是药物化学领域的著名专家。本书共有6个分卷，本版编者为第6版的著作共花费了3年半的时间。共6卷：V.1:药物发现 V.2:药物发现与药物发展 V.3:心血管药物与内分泌 V.4:自体有效物质，诊断，和来源于新生物学的药物 V.5:化疗药物 V.6:神经系统药物 5 g2 w$ R. X; W. J' P
% S3 S, i$ u' r0 V6 W { N
各卷目录与下载地址：
2 S6 K; q; C% ~, r" u* E
3 c7 t5 R' x [* m8 jVolume 1: Drug Discovery% F: j; r( u+ v/ z& ?8 r; o8 `7 u
Contents
. I2 P* M* P" g1 i* X# P6 lHistory of Quantitative Structure Activity Relationships
/ Z8 C- w F3 m% t* p6 q% s! bRecent Trends in QSAR
# m- C- r {2 s8 M5 H9 wMolecular Modeling in Drug Design 4 \& S, R, k B
Drug-Target Binding Forces: Advances in Force Field Approaches
3 Z. E2 a; @* ~Combinatorial Library Design, Molecular Similarity and Diversity Applications 7 r( O- z9 \& g1 L$ |
Virtual Screening
8 s3 @" H& Y" Q; E* iDocking and Scoring Functions/Virtual Screening
5 v# ^# S( J+ l( XBioinformatics
- G) p/ a9 M7 ~Chemical Information Computing Systems $ K1 u- Q. I7 u8 c* f9 z; X2 B/ w+ k
X-ray Crystallography
9 g8 {2 w2 {+ d7 n2 Q4 |NMR and Drug Discovery / e3 t P) [+ |( C. f) |
Mass Spectrometry and Drug Discovery
2 |3 Y9 {; B$ L1 N6 I; eElectron Cryomicroscopy of Biological Macromolecules * S2 `7 ^+ B1 D1 O% s6 _
Design of Peptidomimetics ! ]+ I2 |4 l( _$ _
Analog Design ) B6 ~2 M. c; @( J. x: i
Approaches to the Rational Design of Enzyme Inhibitors
( M7 {' m+ s9 ]8 k1 c0 RChirality and Biological Activity
# Z2 b3 Z. ^; E/ X0 V' p1 t9 `Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents ' A" g& A: D' F2 W# j, g# G
Natural Products as Leads for New Pharmaceuticals4 \" p' P. c8 i/ u9 |; U) m
Index& {9 z# e) p' k% B ?; d- }
1,125 pages 9 r3 m H8 b/ D, c
, R, C+ m8 o& ]# O
下载地址：7 B8 X) h& z5 V4 I& Y; V
http://rapidshare.com/files/9526 ... covery_6Ed_Vol1.pdf
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! V+ Z; a( M( B$ }; i4 T; W# a, \$ }Volume 2: Discovery and Drug Development
: q- U7 l( K" W( gContents& C& ]! _, A. ]6 g) O% W2 Y m
Combinatorial Chemistry and Multiple Parallel Synthesis
- i2 ]9 [# L0 J2 r9 S, eHigh-Throughput Screening for Lead Discovery % a' h* G& }9 M E* s5 I
High-Throughput Pharmacology $ W/ u; _. y4 W( f+ ?$ D" T
Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery , r4 J& t1 V4 U u, ?3 N( ]
Oligonucleotide Therapeutics
& V4 q3 r/ Q; q0 M/ HTherapeutic Agents Acting on RNA
) q5 B5 l; M" x# wCarbohydrate-Based Therapeutics ' {; \; T$ _4 y, U9 x3 U* z6 }
Membrane Transport Proteins and Drug Transport
! p" Y# F1 H) Z3 c @5 i* r$ ZAllosteric Proteins and Drug Discovery S; w* |* I3 |
Receptor Targets in Drug Discovery and Development
2 V: t+ p( l" n& ?1 a- K; v i1 x5 ONicotinic Acetylcholine Receptors % K: |! M8 G: Y% J: C" D& v
Large-Scale Synthesis
: T) ]- w5 o7 `: E* `" fPrinciples of Drug Metabolism
7 b# f& K# O' l6 eMetabolic Considerations in Prodrug Design
! r5 K+ B; l% A. r/ d9 z7 h1 s2 NRetrometabolism-Based Drug Design and Targeting
' ?& n- }9 A$ dDrug Discovery: The Role of Toxicology
/ b* a! J' J6 e2 ^6 U# rDrug Absorption, Distribution, and Elimination : C7 R u' c/ o
Physicochemical Characterization and Principles of Oral Dosage Form Selection
6 Q' c& k+ k& B% v& F" H. e+ G$ o9 a8 YThe FDA and Regulatory Issues 7 x9 D' ~4 v- ^8 ?, b' ]- o( \
Intellectual Property in Drug Discovery and Biotechnology/ N: A' U$ h( H3 N
Index
/ ?8 Y6 I( [4 J4 F+ ?. x808 pages
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6 p8 U( l& E6 x) B' H. _8 P5 E下载地址：% M: M( x0 c+ M; ]
http://rapidshare.com/files/9552 ... covery_6Ed_Vol2.pdf
2 y0 s: r. Y5 P$ j* Z0 u/ ~" \9 x+ v
0 ^: J( Q4 r- y: SVolume 3: Cardiovascular Agents and Endocrine1 Y- g3 _& p0 |% u i
Contents' d$ }" V5 b; D: @ g5 x
Cardiac Drugs + \$ j* [% C6 O7 ?* Z
Diuretic and Uricosuric Agents
3 k$ i5 a0 c- B; Q& DMyocardial Infarction Agents : l4 q- u1 F. J: `5 L* ^- v: ]
Endogenous Vasoactive Peptides
# E0 ?8 n; a/ M; BHematopoietic Agents
4 Q" a# x0 x# F6 ?: |) VAnticoagulants, Antithrombotics, and Hemostatics
' m: z+ i: k+ L, @7 bAntihyperlipedemic Agents ' _* r7 P7 y6 k! a$ ?
Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, Plasma Expanders
' s! T, a& A Y5 F8 C3 h4 V3 QInhibition of Sickle Hemoglobin Polymerization as a Basis For Therapeutic Approach to Sickle-Cell Anemia
. V1 @2 o9 ^+ mIron Chelators
8 |* `6 D( _9 G* ^5 m- G9 fThyroid Hormones and Thyromimetics
4 Q, A8 h) c" c7 a% j* A% Y) TFundamentals of Steroid Chemistry and Biochemistry ) y% B+ o; v* k$ @ M. L" h
Female Sex Hormones, Contraceptives and Fertility Drugs " k# u# p! Z5 o9 T/ |2 }8 k
Male Sex Hormones, Analogs and Antagonists 6 [; U* i2 d" S' p( `$ G
Anti-inflammatory Steroids( e( h% I9 O/ g0 Y
Index' Q3 X1 T* v# J
912 pages9 C; x( ^: F5 X1 s7 V$ M8 O
t! q8 e! H# {( E. I
下载地址：/ g _1 y0 [) K! e4 ]6 E3 U4 ]6 E
http://rapidshare.com/files/9552 ... covery_6Ed_Vol3.pdf
6 F9 _( n8 U$ U( v) U' I w, ^* O$ R1 p; Y4 T: Y
Volume 4: Autocoids, Diagnostics, and Drugs from New Biology$ ~2 q/ E, j# C8 k2 m9 u3 ]
Contents
8 Y p ^# M; Q7 KInsulin and Hypoglycemic Agents
' j7 Y+ v) l5 k6 g' Z" M- FPeptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents
* Q- z1 ?8 l5 D/ L9 g6 IInhibitors of Gastric Acid Secretion 4 M# t) H4 T& X. S1 c1 S
Chemokines and Cytokine Modulators
) W: U. I: G8 ?( _2 SCOX-2 Inhibitors and Leukotriene Modulators : l% |. e" c) D8 \/ u6 E
Agents Acting on Prostanoid Receptors
. [' U+ M/ `) BRetinoids
% y$ R* ^+ e, r6 _* Z! {Vitamins
0 w6 Q! c; a( M1 @, }& x+ n* uLife Style and Over-the-Counter Drugs
7 L6 n: F- ?. U" K5 C7 Z9 tRadiopaques R2 @4 y* K, F& |+ F
Microarrays and Gene Expression Profiling Applied to Drug Research
1 V3 j- r' @: p& y- ASNPs: Single Nucleotide Polymorphisms and Pharmacogenomics ) i( N2 r( t' i& N, U# X8 p4 P8 A
Plasmid DNA-Mediated Gene Therapy
7 ~* T0 w* T% N; {- \1 h' B" x702 pages6 v* `# M8 D. j2 Z* g
3 K7 M8 ~& A) F/ b5 ^+ {- g
下载地址：
3 X4 B* | @; h0 O8 _http://rapidshare.com/files/9552 ... covery_6Ed_Vol4.pdf
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Volume 5: Chemotherapeutic Agents
( U4 f$ Z$ I3 W( Z8 |Contents' J0 P) X& c) \* W
Molecular Biology of Cancer
2 m/ W$ q+ P% W- O; ~" A/ LSynthetic DNA-Targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs
' L# q) Z4 q# kAntitumor Natural Products + p+ e' N$ J5 F+ k8 s2 R& \
Radiosensitizers and Radioprotective Agents
% W9 W" G5 y& S- HSynthetic Anti-angiogenic Agents
$ L! J' ^! e# A' W8 DFuture Strategies in Immunotherapy ) g. t; I+ ]6 h' h; P2 P
Selective Toxicity # ^9 E$ R# z: v+ e, P, H
Drug Resistance in Cancer Chemotherapy + g/ W; q# P! Q; e6 l' t' C
Antiviral Agents, DNA
4 r$ H& l6 t* Z2 `6 \Antiviral Agents, RNA Viruses and Orthopoxviruses
u4 f7 J( I& R; f, a [+ d# zRationale of Design of Anti-HIV Drugs 4 {! k& |. _7 r: ]) Q" p# f
Organ Transplant Drugs 4 W) I4 b% q& ~" J% L
Synthetic Antibacterial Agents $ [5 w$ d0 x; p% @. [
Lactam Antibiotics 1 d: K0 S: D# V5 f8 V( [
Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics 2 @0 h$ q, ?, j$ Z( `" `
Antimycobacterial Agents
! v8 f. C" g# a t& AAntifungal Agents
6 G8 V/ a/ v2 w$ X, vAntimalarial Agents
9 m( `( w9 Z' Y! X) T# CAntiprotozoal Agents
( ^( z. C6 e5 r s$ Q* jAnthelmintics- P/ I. ?& L5 k7 E
Index0 v$ ?) s0 b i* u# {
808 pages. x3 u" R" @, L5 u8 p0 E
: Z& U" T+ V2 Z下载地址：2 u9 D1 m$ [# H- O% L, u
http://rapidshare.com/files/9552 ... covery_6Ed_Vol5.pdf
3 d7 O1 r* h3 {7 v$ | { e
9 W) d$ ^: |0 G2 y# a& C3 ?& nVolume 6: Nervous System Agents* A+ F. o6 e$ K. \. j
Contents
! p. N Y; d* U9 t0 mAndrenergics and Andrenergic-Blocking Agents 4 }& w5 a! T2 `" a1 v, T. a
Cholinergics $ ^2 g3 z$ ^9 Q& p( y
Anticholinergic Drugs 1 n: W! Z9 J+ }
CNS Stimulants
# O3 | U, V6 k# l& g0 rSedatives-Hypnotics 9 B$ b. }" T: O
Anticonvulsants
5 R1 J! `( m; T" ENarcotic Analgesics
2 T7 i6 `6 w( n. L( q" J7 }4 C! @Antidepressants ' X, H& r8 b2 j6 Z: Z
Antianxiety Agents 7 S9 W" I+ a0 ^' X
Antipsychotic Agents + R) U' m# Y" ]% q* a6 h
Investigative Agents for use in Neurodegenerative Conditions
, |) |+ c3 y& V! nTherapeutic and Diagnostic Agents for Parkinson抯 Disease , [0 N0 t6 G7 j+ m
Alzheimer抯 Disease: Search for Therapeutics
& a: v2 h* S7 p9 x! A- {0 dCognition Enhancers ) \# B. l- V. }8 O. k# L) @+ Y
Drugs to Treat Eating and Body Weight Disorders
7 Y; {9 [( ^9 O+ ^' N7 P3 |Index
# ~1 X* l4 E) _3 r5 \ G1,084 pages
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下载地址：
8 G! v+ V7 t5 t7 Khttp://rapidshare.com/files/9557 ... covery_6Ed_Vol6.pdf |
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人生百年有几，念良辰美景，休放虚过。穷通前定，何用苦张罗。 |
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发表于 2008-5-27 09:04 AM
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